Only Black Soul Gems can hold the souls of humans. Note that most Soul Gems can only hold the souls of living creatures. If you have several Soul Gems, the creatures soul will be stored in the smallest gem that can hold it. If you have an empty Soul Gem in your inventory that can hold the creature's soul, the soul will be bound to the gem. To fill a soul gem, cast the Soul Trap spell on a creature, then kill it before the spell wears off. The larger the stone, the larger the soul it can store, although larger gems can also hold smaller souls. Filled soul gems are used to create and recharge enchanted items while empty soul gems are used in a number of Atronach Forge Recipes.
Soul Gems are stones that can store the souls of living creatures.